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Ku70 Rabbit mAb

Anti-Ku70 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263399

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263399
产品全名:   Ku70 兔单克隆抗体
基因符号   XRCC6; G22P1; X-ray repair cross-complementing protein 6; 5′-deoxyribose-5-phosphate lyase Ku70; 5′-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-
UNIPROT ID:   P12956
背景:   It works in the 3′-5′ direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic subunit PRKDC to DNA by 100-fold. The XRCC5/6 dimer is probably involved in stabilizing broken DNA ends and bringing them together.
抗原:   A synthetic peptide of human Ku70
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R05-1A7
分子量:   Calculated MW: 70 kDa; Observed MW: 70 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Ku70 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of Ku70 (green) in CEM using Ku70 antibody,and DAPI(blue).

Western blot analysis of Ku70 in Hela, A549, MCF-7, U251 lysates using Ku70 antibody.
           引用文献