| 货号: S222301 |
| 产品全名: KIAA0556 兔多抗 |
| 基因符号 JBTS26 |
| UNIPROT ID: O60303 (Gene Accession – NP_056017 ) |
| 背景: This gene encodes a novel, evolutionarily conserved, ciliary protein. In human hTERT-RPE1 cells, the protein is found at the base of cilia, decorating the ciliary axoneme, and enriched at the ciliary tip. The protein binds to microtubules in vitro and regulates their stability when it is overexpressed. A null mutation in this gene has been associated with Joubert syndrome, a recessive disorder that is characterized by a distinctive mid-hindbrain and cerebellar malformation and is also often associated with wider ciliopathy symptoms. Consistently, in a serum-starvation ciliogenesis assay, human fibroblast cells derived from patients with the mutation display a reduced number of ciliated cells with abnormally long cilia. |
| 抗原: Synthetic peptide of human KIAA0556 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 100-200; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 222301(KIAA0556 Antibody) at a dilution of 1/90(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 222301(Anti-KIAA0556 Antibody) at dilution 1/90. | 
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 222301(Anti-KIAA0556 Antibody) at a dilution of 1/90. | 
In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with synthetic peptide and then with D264358(Anti-KIAA0556 Antibody) at dilution 1/90. |
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