武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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KDM6B Rabbit pAb

Anti-KDM6B Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S213822

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S213822
产品全名:   KDM6B 兔多抗
基因符号   JMJD3; NEDCFSA
UNIPROT ID:   O15054 (Gene Accession – NP_001073893 )
背景:   The protein encoded by this gene is a lysine-specific demethylase that specifically demethylates di- or tri-methylated lysine 27 of histone H3 (H3K27me2 or H3K27me3). H3K27 trimethylation is a repressive epigenetic mark controlling chromatin organization and gene silencing. This protein can also demethylate non-histone proteins such as retinoblastoma protein. Through its demethylation actvity this gene influences cellular differentiation and development, tumorigenesis, inflammatory diseases, and neurodegenerative diseases. This protein has two classical nuclear localization signals at its N-terminus. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
抗原:   Synthetic peptide of human KDM6B
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-100; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 213822(KDM6B Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the synthetic peptide and then with 213822(Anti-KDM6B Antibody) at dilution 1/50.
           引用文献