武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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KDM5B Rabbit pAb

Anti-KDM5B Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S214435

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S214435
产品全名:   KDM5B 兔多抗
基因符号   CT31; PLU1; PUT1; PLU-1; JARID1B; RBBP2H1A
UNIPROT ID:   Q9UGL1 (Gene Accession – NP_006609 )
背景:   PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.
抗原:   Synthetic peptide of human KDM5B
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 214435(KDM5B Antibody) at a dilution of 1/40(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the synthetic peptide and then with 214435(Anti-KDM5B Antibody) at dilution 1/40.
           引用文献