武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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KDM2A Rabbit mAb

Anti-KDM2A Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262212

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262212
产品全名:   KDM2A 兔单克隆抗体
基因符号   FBL7; CXXC8; FBL11; FBXL11; JHDM1A; LILINA
UNIPROT ID:   Q9Y2K7
背景:   Histone demethylase that specifically demethylates ‘Lys-36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ‘Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ‘Lys-36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
抗原:   A synthetic peptide of human FBXL11
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R05-4D6
分子量:   Calculated MW: 133 kDa; Observed MW: 133 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of FBXL11 in Jurkat lysates using KDM2A antibody.
           引用文献