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kappa Opioid Receptor Rabbit mAb

Anti-kappa Opioid Receptor Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262439

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262439
产品全名:   kappa Opioid Receptor 兔单克隆抗体
基因符号   KOR; R21; KOR-1; MSL-1; Oprk2; K-OR-1
UNIPROT ID:   P33534
背景:   G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.
抗原:   A synthetic peptide of mouse Kappa Opioid Receptor
经过测试的应用:   WB,IP
推荐稀释比:   WB: 1/500-1/1000 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R03-2A5
分子量:   Calculated MW: 43 kDa; Observed MW: 60 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Kappa Opioid Receptor in rat Brain lysates using kappa Opioid Receptor antibody.
           引用文献