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IFI35 Rabbit pAb

Anti-IFI35 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S215985

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S215985
产品全名:   IFI35 兔多抗
基因符号   IFP35
UNIPROT ID:   P80217 (Gene Accession – NP_001317159 )
背景:   The Interferon family of proteins are able to alter the expression of a variety of target genes, thereby controlling various events within the cell. IFI-35 (Interferon-induced 35 kDa protein), also known as IFP35, is a 286 amino acid interferon-induced protein. Localized to the nucleus and expressed in macrophages, fibroblasts and epithelial cells, IFI-35 is a leucine zipper protein that can form homodimers, but, unlike most leucine zipper proteins, cannot bind DNA. Upon induction by IFN-à, IFI-35 associates with Nmi (N-Myc-interacting protein), resulting in the formation of a high molecular weight complex that is thought to play a role in IFN-à signaling and cellular responses. Once complexed with Nmi, IFI-35 is unable to be degraded by the proteasome, suggesting that IFI-35 is protected from degradation only when needed by IFN-à. Two isoforms of IFI-35 exist due to alternative splicing events.
抗原:   Synthetic peptide of human IFI35
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 215985(IFI35 Antibody) at a dilution of 1/35(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 215985(Anti-IFI35 Antibody) at dilution 1/35.
           引用文献