武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

HUWE1 Rabbit pAb

Anti-HUWE1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221491

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221491
产品全名:   HUWE1 兔多抗
基因符号   MULE; Ib772; LASU1; UREB1; HECTH9; URE-B1; ARF-BP1; HSPC272
UNIPROT ID:   Q7Z6Z7 (Gene Accession – NP_113584 )
背景:   This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related)). This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation.
抗原:   Synthetic peptide of human HUWE1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: Oct-50; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 221491(HUWE1 Antibody) at a dilution of 1/30(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 221491(Anti-HUWE1 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 221491(Anti-HUWE1 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D263109(Anti-HUWE1 Antibody) at dilution 1/30.
           引用文献