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HP1 alpha (3G2) Mouse mAb

Anti-HP1 alpha (3G2) Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261010

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261010
产品全名:   HP1 alpha (3G2) 小鼠单抗
基因符号   CBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
UNIPROT ID:   P45973
背景:   Component of heterochromatin that recognizes and binds histone H3 tails methylated at ‘Lys-9’ (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when ‘Tyr-41’ of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
抗原:   Purified recombinant human HP1 alpha protein fragments expressed in E.coli.
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   3G2-H10-A6
分子量:   Calculated MW: 22 kDa; Observed MW: 26 kDa
亚型:   IgG2b
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of HP1 alpha (3G2) in Hela using HP1 alpha antibody.

Western blot analysis of HP1 alpha in MCF-7, 293T, 3T3, C6, COS7 and mouse brain lysates using HP1 alpha antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using HP1 alpha antibody(3G2).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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