| 货号: S217442 |
| 产品全名: FGFR1OP 兔多抗 |
| 基因符号 FOP |
| UNIPROT ID: O95684 (Gene Accession – BC011902 ) |
| 背景: This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn’s disease, Graves’ disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified. |
| 抗原: Fusion protein of human FGFR1OP |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 50-200;WB: 500-2000;ELISA: 2000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cell Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human brain tissue using 217442(FGFR1OP Antibody) at a dilution of 1/40(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 217442(Anti-FGFR1OP Antibody) at dilution 1/40. | 
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 217442(Anti-FGFR1OP Antibody) at a dilution of 1/40. | 
In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with fusion protein and then with D222365(Anti-FGFR1OP Antibody) at dilution 1/40. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Mouse heart tissue, NIH/3T3 cells, mouse liver tissue;
Primary antibody: 217442(FGFR1OP Antibody) at dilution 1/850;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 2 minutes | |
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