| 货号: S219110 |
| 产品全名: FDPS 兔多抗 |
| 基因符号 FPS; FPPS; POROK9 |
| UNIPROT ID: P14324 (Gene Accession – BC010004 ) |
| 背景: This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene. |
| 抗原: Fusion protein of human FDPS |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 50-300; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Metabolism, Cancer, Cardiovascular |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219110(FDPS Antibody) at a dilution of 1/60(Cytoplasm and Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 219110(Anti-FDPS Antibody) at dilution 1/60. | 
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 219110(Anti-FDPS Antibody) at a dilution of 1/60. | 
In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with fusion protein and then with D225861(Anti-FDPS Antibody) at dilution 1/60. |
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