| 货号: S219763 |
| 产品全名: ESR1 兔多抗 |
| 基因符号 ER, ESR, Era, ESRA, NR3A1 |
| UNIPROT ID: P03372 (Gene Accession – NP_000116 ) |
| 背景: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5′ UTRs and use different promoters. |
| 抗原: Synthetic peptide of human ESR1 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 100-300; ELISA: 1000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Epigenetics and Nuclear Signaling, Neuroscience |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human brain tissue using 219763(ESR1 Antibody) at a dilution of 1/76(Cytoplasm, Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the synthetic peptide and then with 219763(Anti-ESR1 Antibody) at dilution 1/76. | 
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 219763(Anti-ESR1 Antibody) at a dilution of 1/76. | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with synthetic peptide and then with D260314(Anti-ESR1 Antibody) at dilution 1/76. |
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