武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ENG Rabbit pAb

Anti-ENG Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217249

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217249
产品全名:   ENG 兔多抗
基因符号   END; HHT1; ORW1
UNIPROT ID:   P17813 (Gene Accession – BC014271 )
背景:   This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
抗原:   Fusion protein of human ENG
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 100-200;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Cancer, Cardiovascular, Immunology, Stem Cells
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 217249(ENG Antibody) at a dilution of 1/80(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 217249(Anti-ENG Antibody) at dilution 1/80.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: HepG2, Jurkat and MCF-7 cell lysates;
Primary antibody: 217249(ENG Antibody) at dilution 1/650;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
           引用文献