| 货号: S216489 |
| 产品全名: ELAVL1 兔多抗 |
| 基因符号 HUR; Hua; MelG; ELAV1 |
| UNIPROT ID: Q15717 (Gene Accession – BC003376 ) |
| 背景: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy. |
| 抗原: Fusion protein of human ELAVL1 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 500-2000;ELISA: 2000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216489(ELAVL1 Antibody) at a dilution of 1/50(Nucleus and Cytoplasm ). | 
In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216489(Anti-ELAVL1 Antibody) at dilution 1/50. | 
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 216489(Anti-ELAVL1 Antibody) at a dilution of 1/50. | 
In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D220589(Anti-ELAVL1 Antibody) at dilution 1/50. | 
Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: Hela cells, NIH/3T3 cells, A172 cells, A431 cells;
Primary antibody: 216489(ELAVL1 Antibody) at dilution 1/800;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 seconds | |
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