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EIF3H Rabbit pAb

Anti-EIF3H Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217390

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217390
产品全名:   EIF3H 兔多抗
基因符号   EIF3S3; eIF3-p40; eIF3-gamma
UNIPROT ID:   O15372 (Gene Accession – BC000386 )
背景:   Component of the eukaryotic translation initiation factor 3 (eIF-3) comple,x which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
抗原:   Fusion protein of human EIF3H
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human esophagus cancer tissue using 217390(EIF3H Antibody) at a dilution of 1/50(Cytoplasm).

Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer tissue using 217390(Anti-EIF3H Antibody) at a dilution of 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Human adrenal pheochromocytoma and fetal brain tissue;
Primary antibody: 217390(EIF3H Antibody) at dilution 1/1150;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 40 seconds
           引用文献