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DOCK8 Rabbit mAb

Anti-DOCK8 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262146

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262146
产品全名:   DOCK8 兔单克隆抗体
基因符号   MRD2; ZIR8; HEL-205
UNIPROT ID:   Q8NF50
背景:   Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP (PubMed:28028151, PubMed:22461490). During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC . Required for CD4+ T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane (PubMed:28028151). Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing center (MTOC), and possibly regulating CCDC88B-mediated lytic granule transport to MTOC during cell killing (PubMed:25762780).
抗原:   Recombinant protein of human DOCK8
经过测试的应用:   WB,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R05-7D3
分子量:   Calculated MW: 239 kDa; Observed MW: 239 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cardiovascular
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of DOCK8 in Ramos lysates using DOCK8 antibody.
           引用文献