武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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DNMT3A Rabbit pAb

Anti-DNMT3A Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S217054

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S217054
产品全名:   DNMT3A 兔多抗
基因符号   DNMT3A2; M.HsaIIIA
UNIPROT ID:   Q9Y6K1 (Gene Accession – BC043617 )
背景:   CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms.
抗原:   Fusion protein of human DNMT3A
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 217054(DNMT3A Antibody) at a dilution of 1/50(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 217054(Anti-DNMT3A Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using 217054(Anti-DNMT3A Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with fusion protein and then with D221710(Anti-DNMT3A Antibody) at dilution 1/50.
           引用文献