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COPS5 Rabbit pAb

Anti-COPS5 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S210411

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S210411
产品全名:   COPS5 兔多抗
基因符号   CSN5, JAB1, SGN5, MOV-34
UNIPROT ID:   Q92905 (Gene Accession – BC001187 )
背景:   The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors
抗原:   Fusion protein of human COPS5
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 150-500;WB: 1000-5000;ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 210411(COPS5 Antibody) at a dilution of 1/120(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 210411(Anti-COPS5 Antibody) at dilution 1/120.

Gel: 12%SDS-PAGE, Lysate: 30 μg;
Lane: Mouse liver tissue;
Primary antibody: 210411(COPS5 Antibody) at dilution 1/1550;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 seconds
           引用文献