武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CDC45 Rabbit pAb

Anti-CDC45 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218454

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218454
产品全名:   CDC45 兔多抗
基因符号   CDC45L; MGORS7; CDC45L2; PORC-PI-1
UNIPROT ID:   O75419 (Gene Accession – BC006232 )
背景:   The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
抗原:   Fusion protein of human CDC45
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218454(CDC45 Antibody) at a dilution of 1/70(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218454(Anti-CDC45 Antibody) at dilution 1/70.
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