| 货号: S216372 |
| 产品全名: BMP4 兔多抗 |
| 基因符号 ZYME; BMP2B; OFC11; BMP2B1; MCOPS6 |
| UNIPROT ID: P12644 (Gene Accession – BC020546 ) |
| 背景: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers. |
| 抗原: Fusion protein of human BMP4 |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 50-200;WB: 500-2000;ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction, Cancer, Cardiovascular, Developmental Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 216372(BMP4 Antibody) at a dilution of 1/100(Secreted). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 216372(Anti-BMP4 Antibody) at dilution 1/100. | 
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 216372(Anti-BMP4 Antibody) at a dilution of 1/100. | 
In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D220315(Anti-BMP4 Antibody) at dilution 1/100. | 
Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: HT29 cell lysate;
Primary antibody: 216372(BMP4 Antibody) at dilution 1/700;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 5 seconds | |
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