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ABCC2 Rabbit pAb

Anti-ABCC2 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219916

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219916
产品全名:   ABCC2 兔多抗
基因符号   DJS; MRP2; cMRP; ABC30; CMOAT
UNIPROT ID:   Q92887 (Gene Accession – NP_000383 )
背景:   The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
抗原:   Synthetic peptide of human ABCC2
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 30-150; ELISA: 2000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Cancer
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219916(ABCC2 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 219916(Anti-ABCC2 Antibody) at dilution 1/45.
           引用文献