| 货号: S220027 |
| 产品全名: ABCB11 兔多抗 |
| 基因符号 BSEP; PGY4; SPGP; ABC16; BRIC2; PFIC2; PFIC-2 |
| UNIPROT ID: O95342 (Gene Accession – NP_003733 ) |
| 背景: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. |
| 抗原: Synthetic peptide of human ABCB11 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 15-50; ELISA: 1000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Metabolism, Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human ovarian cancer tissue using 220027(ABCB11 Antibody) at a dilution of 1/15(Cytoplasm ). | 
In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with the synthetic peptide and then with 220027(Anti-ABCB11 Antibody) at dilution 1/15. | 
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220027(Anti-ABCB11 Antibody) at a dilution of 1/15. | 
In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D260801(Anti-ABCB11 Antibody) at dilution 1/15. |
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