武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥4,800.00
产品名称: Rac1-GTP 小鼠单抗 |
货号: 货号:: 26903 |
货号: 30 µL |
基因符号: RAC1 |
描述: Anti-Rac1-GTP 单抗 |
背景: Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs). |
Immunogen: Recombinant full length protein of active Rac1 |
经过测试的应用: IP, IHC and IF (Not applicable for WB since WB denatures the GTPase) |
推荐稀释比: IP: 1 µg for 1~2 mg total cellular proteinsIHC, IF: 1:50-1:250 |
Concentration: 1 mg/ml |
种属反应性: Mouse |
形式: Liquid |
克隆性: Monoclonal |
亚型: IgM |
纯化: Purified from ascites |
Preservative: no |
成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
种属反应性: Anti-Rac1-GTP monoclonal antibody recognizes active Rac1 from vertebrates. |
储存条件: Store at -20°C. Avoid repeated freezing and thawing |
免疫沉淀/蛋白质印迹: Immunofluorescence for the active Rac using Anti-Rac1-GTP 小鼠单抗 [26903] shows Rac-GTP immunolabeling (green) in combination with cofilin (red) on brain tissue sections.The tissue sections were fixed with -20 ºC methanol or 4% paraformaldehyde (fixation time 1 hr) and stained with antibody at 1:1000 in 0.1M Phosphate buffer with 0.3% Triton X, and 4% BSA for 24h at room temperature. Secondary antibodies were anti-mouse AlexaFluor488 and anti-rabbit AlexaFluor594 at 1:1000. |
<table>
<tbody>
<tr><td><strong>001. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36584745/” target=”_blank” rel=”noopener”>Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer</a><br/>Exp Cell Res. 2023   PMID: 36584745</td><tr/>
<tr><td><strong>002. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10171644/” target=”_blank” rel=”noopener”>Glucuronoxylomannan intranasal challenge prior to Cryptococcus neoformans pulmonary infection enhances cerebral cryptococcosis in rodents</a><br/>PLoS Pathog. 2023   PMID: 37115795</td><tr/>
<tr><td><strong>003. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/37298689/” target=”_blank” rel=”noopener”>Tumoricidal Activity of Simvastatin in Synergy with RhoA Inactivation in Antimigration of Clear Cell Renal Cell Carcinoma Cells</a><br/>Int J Mol Sci. 2023   PMID: 37298689</td><tr/>
<tr><td><strong>004. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36446524/” target=”_blank” rel=”noopener”>Loss of cell-cell adhesion triggers cell migration through Rac1-dependent ROS generation</a><br/>Life Sci Alliance. 2022   PMID: 36446524</td><tr/>
<tr><td><strong>005. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36598812/” target=”_blank” rel=”noopener”>The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration</a><br/>Life Sci Alliance. 2022   PMID: 36598812</td><tr/>
<tr><td><strong>006. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36744839/” target=”_blank” rel=”noopener”>Rac1 and Rac3 GTPases and TPC2 are required for axonal outgrowth and migration of cortical interneurons</a><br/>J Cell Sci. 2023   PMID: 36744839</td><tr/>
<tr><td><strong>007. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36598812/” target=”_blank” rel=”noopener”>The Scaffold RhoGAP Protein ARHGAP8/ BPGAP1 Synchronizes Rac and Rho Signaling to Facilitate Cell Migration</a><br/>Mol Biol Cell. 2023  PMID: 36598812</td><tr/>
<tr><td><strong>008. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36508052/” target=”_blank” rel=”noopener”>Catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles</a><br/>J Cell Commun Signal. 2022  PMID: 36508052</td><tr/>
<tr><td><strong>009. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36584745/” target=”_blank” rel=”noopener”>Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer</a><br/>Exp Cell Res. 2022  PMID: 36584745</td></tr>
<tr><td><strong>010. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36446524/” target=”_blank” rel=”noopener”>Loss of cell–cell adhesion triggers cell migration through Rac1-dependent ROS generation</a><br/>Life Sci Alliance. 2022  PMID: 36446524</td><tr/>
<tr><td><strong>011. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36508052/” target=”_blank” rel=”noopener”>Catalpol inhibits hepatic stellate cell activation by reducing the formation and changing the contents of hepatocyte-derived extracellular vesicles</a><br/>J Cell Commun Signal. 2022  PMID: 36508052</td><tr/>
<tr><td><strong>012. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9582797/” target=”_blank” rel=”noopener”>Cardiac inducing colonies halt fibroblast activation and induce cardiac/endothelial cells to move and expand via paracrine signaling</a><br/>Mol Biol Cell. 2022  PMID: 35653297</td><tr/>
<tr><td><strong>013. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760284/” target=”_blank” rel=”noopener”>Inhibition of Rac1 attenuates radiation-induced lung injury while suppresses lung tumor in mice</a><br/>Cell Death Discov. 2022  PMID: 35031595</td><tr/>
<tr><td><strong>014. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9305120/” target=”_blank” rel=”noopener”>Smooth muscle Rac1 contributes to pulmonary hypertension</a><br/>BJP. 2022  PMID: 35064565</td><tr/>
<tr><td><strong>015. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35074515/” target=”_blank” rel=”noopener”>Rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification</a><br/>Cardiovasc Pathol. 2022  PMID: 35074515</td><tr/>
<tr><td><strong>016. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35104805/” target=”_blank” rel=”noopener”>A Portable Controllable Compressive Stress Device to Monitor Human Breast Cancer Cell Protrusions at Single-Cell Resolution</a><br/>J Clin Invest. 2022  PMID: 35104805</td><tr/>
<tr><td><strong>017. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8845157/” target=”_blank” rel=”noopener”>Hepatic Ischemia-reperfusion Injury in Mice was Alleviated by Rac1 Inhibition – More Than Just ROS-inhibition</a><br/>J Clin Transl Hepatol. 2022  PMID: 35233372</td><tr/>
<tr><td><strong>018. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8907972/” target=”_blank” rel=”noopener”>Targeting the ASMase/S1P pathway protects from sortilin-evoked vascular damage in hypertension</a><br/>J Neuroinflammation. 2022  PMID: 35284404</td><tr/>
<tr><td><strong>019. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/35420656/” target=”_blank” rel=”noopener”>Planar cell polarity-dependent asymmetric organization of microtubules for polarized positioning of the basal body in node cells</a><br/>Development. 2022  PMID: 35420656</td><tr/>
<tr><td><strong>020. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245039/” target=”_blank” rel=”noopener”>Time of Day-Dependent Alteration of Hippocampal Rac1 Activation Regulates Contextual Fear Memory in Rats</a><br/>Front Mol Neurosci. 2022  PMID: 35782392</td><tr/>
<tr><td><strong>021. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9281167/” target=”_blank” rel=”noopener”>Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor</a><br/>Front Bioeng Biotechnol. 2022  PMID: 35831873</td><tr/>
<tr><td><strong>022. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9308268/” target=”_blank” rel=”noopener”>ARHGEF37 overexpression promotes extravasation and metastasis of hepatocellular carcinoma via directly activating Cdc42</a><br/>J Exp Clin Cancer Res. 2022  PMID: 35869555</td><tr/>
<tr><td><strong>023. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36129975/” target=”_blank” rel=”noopener”>Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery</a><br/>Sci Adv. 2022  PMID: 36129975</td><tr/>
<tr><td><strong>024. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9492659/” target=”_blank” rel=”noopener”>Differential dysregulation of granule subsets in WASH-deficient neutrophil leukocytes resulting in inflammation</a><br/>Nat Commun. 2022  PMID: 36130971</td><tr/>
<tr><td><strong>025. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9496593/” target=”_blank” rel=”noopener”>The Pro-Fibrotic Response to Lens Injury Is Signaled in a PI3K Isoform-Specific Manner</a><br/>Biomolecules. 2022  PMID: 36139020</td><tr/>
<tr><td><strong>026. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9562403/” target=”_blank” rel=”noopener”>Anti-ANGPTL3-FLD monoclonal antibody treatment ameliorates podocyte lesions through attenuating mitochondrial damage</a><br/>Cell Death Dis. 2022  PMID: 36229446</td><tr/>
<tr><td><strong>027. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/36284029/” target=”_blank” rel=”noopener”>Critical role of mitogen-inducible gene 6 in restraining endothelial cell permeability to maintain vascular homeostasis</a><br/>J Cell Commun Signal. 2022  PMID: 36284029</td><tr/>
<tr><td><strong>028. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9599176/” target=”_blank” rel=”noopener”>PTEN Protein Phosphatase Activity Is Not Required for Tumour Suppression in the Mouse Prostate</a><br/>Biomolecules. 2022  PMID: 36291720</td><tr/>
<tr><td><strong>029. </strong><a href=”https://www.sciencedirect.com/science/article/pii/S2667325822001996″ target=” blank” rel=”noopener”>Dock4 is required for the maintenance of cochlear hair cells and hearing function</a><br/>Fundamental Research. 2022</td></tr>
<tr><td><strong>030. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7927959/” target=”_blank” rel=”noopener”>A role of PIEZO1 in iron metabolism in mice and humans.</a><br/>Cell. 2021  PMID: 33571427</td><tr/>
<tr><td><strong>031. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33397922/” target=”_blank” rel=”noopener”>A RAC-GEF network critical for early intestinal tumourigenesis</a><br/>Nat Commun. 2021  PMID: 33397922</td><tr/>
<tr><td><strong>032. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33527537/” target=” blank” rel=”noopener”>Arhgef6 (alpha-PIX) cytoskeletal regulator signals to GTPases and Cofilin to couple T cell migration speed and persistence</a><br/>J Leukoc Biol. 2021  PMID: 33527537</td><tr/>
<tr><td><strong>033. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7982925/” target=”_blank” rel=”noopener”>Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling</a><br/>Thorax. 2021  PMID: 33542087</td><tr/>
<tr><td><strong>034. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8865553/” target=”_blank” rel=”noopener”>7-ketocholesterol induces endothelial-mesenchymal transition and promotes fibrosis: implications in neovascular age-related macular degeneration and treatment</a><br/>Angiogenesis. 2021  PMID: 33646466</td><tr/>
<tr><td><strong>035. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33852856/” target=”_blank” rel=”noopener”> Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress</a><br/>Cell Rep. 2021  PMID: 33852856</td><tr/>
<tr><td><strong>036. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8085119/” target=”_blank” rel=”noopener”>Apoptotic cells in mouse blastocysts are eliminated by neighbouring blastomeres</a><br/>Sci Rep. 2021  PMID: 33927296</td><tr/>
<tr><td><strong>037. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/33973520/” target=”_blank” rel=”noopener”> EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice</a><br/>eLife. 2021  PMID: 33973520</td><tr/>
<tr><td><strong>038. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483510/” target=”_blank” rel=”noopener”>MFG‐E8 Regulates Vascular Smooth Muscle Cell Migration Through Dose‐Dependent Mediation of Actin Polymerization</a><br/>J Am Heart Assoc. 2021  PMID: 34041925</td><tr/>
<tr><td><strong>039. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8276982/” target=”_blank” rel=”noopener”>Hydrostatic mechanical stress regulates growth and maturation of the atrioventricular valve</a><br/>Development. 2021  PMID: 34086041</td><tr/>
<tr><td><strong>040. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34212532/” target=” blank” rel=”noopener”>Flexible Ultrasonic Patch for Accelerating Chronic Wound Healing</a><br/>Adv Healthc Mater. 2021  PMID: 34212532</td><tr/>
<tr><td><strong>041. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8452869/” target=”_blank” rel=”noopener”>Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development</a><br/>Front Cell Dev Biol. 2021  PMID: 34557485</td><tr/>
<tr><td><strong>042. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8604770/” target=”_blank” rel=”noopener”>Decoupling Tumor Cell Metastasis From Growth By Cellular Pilot Protein TNFAIP8</a><br/>Oncogene. 2021  PMID: 34608264</td><tr/>
<tr><td><strong>043. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34626585/” target=” blank” rel=”noopener”>Scavenger receptor MARCO contributes to macrophage phagocytosis and clearance of tumor cells</a><br/>Exp Cell Res. 2021  PMID: 34626585</td><tr/>
<tr><td><strong>044. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8595285/” target=”_blank” rel=”noopener”>Geranylgeraniol Restores Zoledronic Acid-Induced Efferocytosis Inhibition in Bisphosphonate-Related Osteonecrosis of the Jaw</a><br/>Front Cell Dev Biol. 2021  PMID: 34805177</td><tr/>
<tr><td><strong>045. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/34880503/” target=”_blank” rel=”noopener”>Collective durotaxis along a self-generated stiffness gradient in vivo</a><br/>Nature. 2021  PMID: 34880503</td><tr/>
<tr><td><strong>046. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8712650/” target=”_blank” rel=”noopener”>Sustained Release of Gas6 via mPEG-PLGA Nanoparticles Enhances the Therapeutic Effects of MERTK Gene Therapy in RCS Rats</a><br/>Front Med (Lausanne). 2021  PMID: 34970569</td><tr/>
<tr><td><strong>047. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8733199/” target=”_blank” rel=”noopener”>yk-MyD88 Axis Is a Critical Determinant of Inflammatory-Response in Activated Macrophages</a><br/>Front Immunol. 2021  PMID: 35003083</td><tr/>
<tr><td><strong>048. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6973152/” target=”_blank” rel=”noopener”>Voltage‐dependent activation of Rac1 by Nav1.5 channels promotes cell migration</a><br/>J Cell Physiol. 2020  PMID: 31612502</td><tr/>
<tr><td><strong>049. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020796/” target=”_blank” rel=”noopener”>Dysregulation of Rac or Rho elicits death of motor neurons and activation of these GTPases is altered in the G93A mutant hSOD1 mouse model of amyotrophic lateral sclerosis</a><br/>Neurobiol Dis. 2020  PMID: 31931138</td><tr/>
<tr><td><strong>050. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7082877/” target=”_blank” rel=”noopener”>Statins Disrupt Macrophage Rac1 Regulation Leading to Increased Atherosclerotic Plaque Calcification</a><br/>Arterioscler Thromb Vasc Biol. 2020  PMID: 31996022</td><tr/>
<tr><td><strong>051. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992649/” target=”_blank” rel=”noopener”>Spaced Training Enhances Contextual Fear Memory via Activating Hippocampal 5-HT2A Receptors</a><br/>Front Mol Neurosci. 2020  PMID: 32038159</td><tr/>
<tr><td><strong>052. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7289320/” target=”_blank” rel=”noopener”>Glycolysis Independent Glucose Metabolism Distinguishes TE from ICM Fate During Mammalian Embryogenesis</a><br/>Dev Cell. 2020  PMID: 32197068</td><tr/>
<tr><td><strong>053. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7125138/” target=”_blank” rel=”noopener”>Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation</a><br/>Nat Commun. 2020  PMID: 32246016</td><tr/>
<tr><td><strong>054. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7170861/” target=” blank” rel=”noopener”>The TIPE Molecular Pilot That Directs Lymphocyte Migration in Health and Inflammation</a><br/>Sci Rep. 2020  PMID: 32313148</td><tr/>
<tr><td><strong>055. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/32314182/” target=”_blank” rel=”noopener”>Rac1 activation in human breast carcinoma as a prognostic factor associated with therapeutic resistance</a><br/>Breast Cancer. 2020  PMID: 32314182</td><tr/>
<tr><td><strong>056. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/32320683/” target=”_blank” rel=”noopener”>Rac1-dependent phagocytosis of apoptotic cells by oral squamous cell carcinoma cells: A possible driving force for tumor progression</a><br/>Experimental Cell Research. 2020  PMID: 32320683</td><tr/>
<tr><td><strong>057. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353033/” target=”_blank” rel=”noopener”>PGI2 Analog Attenuates Salt-Induced Renal Injury through the Inhibition of Inflammation and Rac1-MR Activation</a><br/>Int J Mol Sci. 2020  PMID: 32580367</td><tr/>
<tr><td><strong>058. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/32592615/” target=” blank” rel=”noopener”>The laminin-211-derived PPFEGCIWN motif accelerates wound reepithelialization and increases phospho-FAK-Tyr397 and Rac1-GTP levels in a rat excisional wound splinting model</a><br/>J Tissue Eng Regen Med. 2020  PMID: 32592615</td><tr/>
<tr><td><strong>059. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7380942/” target=”_blank” rel=”noopener”>Periodic propagating waves coordinate RhoGTPase network dynamics at the leading and trailing edges during cell migration</a><br/>eLife. 2020  PMID: 32705984</td><tr/>
<tr><td><strong>060. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7530064/” target=” blank” rel=”noopener”>TIQGAP1 Causes Choroidal Neovascularization by Sustaining VEGFR2-mediated Rac1 Activation</a><br/>Angiogenesis. 2020  PMID: 32783108</td><tr/>
<tr><td><strong>061. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491649/” target=”_blank” rel=”noopener”>Mitofusin 2 regulates neutrophil adhesive migration and the actin cytoskeleton</a><br/>J Cell Sci. 2020  PMID: 32788232</td><tr/>
<tr><td><strong>062. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30659265/” target=” blank” rel=”noopener”>Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells</a><br/>Oncogene. 2019  PMID: 30659265</td><tr/>
<tr><td><strong>063. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543538/” target=”_blank” rel=”noopener”>The trafficking protein JFC1 regulates Rac1-GTP localization at the uropod controlling neutrophil chemotaxis and in vivo migration</a><br/>J Leukoc Biol. 2019  PMID: 30748033</td><tr/>
<tr><td><strong>064. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30788390/” target=”_blank” rel=”noopener”>Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82</a><br/>Bone Reports. 2019  PMID: 30788390</td><tr/>
<tr><td><strong>065. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30797592/” target=” blank” rel=”noopener”>Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis</a><br/>Gynecol Oncol. 2019  PMID: 30797592</td><tr/>
<tr><td><strong>066. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30833420/” target=” blank” rel=”noopener”>Epigenetic Regulation of the PTEN-AKT-RAC1 Axis by G9a Is Critical for Tumor Growth in Alveolar Rhabdomyosarcoma</a><br/>Cancer Res. 2019  PMID: 30833420</td><tr/>
<tr><td><strong>067. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447549/” target=”_blank” rel=”noopener”>In vivo topology converts competition for cell-matrix adhesion into directional migration</a><br/>Nat Commun. 2019  PMID: 30944331</td><tr/>
<tr><td><strong>068. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429438/” target=”_blank” rel=”noopener”>Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling</a><br/>Int J Mol Sci. 2019  PMID: 30866434</td><tr/>
<tr><td><strong>069. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31219639/” target=” blank” rel=”noopener”>Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract</a><br/>Dev Dyn. 2019  PMID: 31219639</td><tr/>
<tr><td><strong>070. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629836/” target=”_blank” rel=”noopener”>TUFT1 Promotes Triple Negative Breast Cancer Metastasis. Stemness. and Chemoresistance by Up-Regulating the Rac1/β-Catenin Pathway</a><br/>Front Oncol. 2019  PMID: 31338333</td><tr/>
<tr><td><strong>071. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31410004/” target=”_blank” rel=”noopener”>Simvastatin pretreatment ameliorates t-PA–induced hemorrhage transformation and MMP-9/TIMP-1 imbalance in thromboembolic cerebral ischemic rats</a><br/>Neuropsychiatr Dis Treat. 2019  PMID: 31410004</td><tr/>
<tr><td><strong>072. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31413255/” target=”_blank” rel=”noopener”>PTPσ inhibitors promote hematopoietic stem cell regeneration</a><br/>Nature Communications. 2019  PMID: 31413255</td><tr/>
<tr><td><strong>073. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31529802/” target=” blank” rel=”noopener”>Quercetin Mitigates Hepatic Insulin Resistance in Rats with Bile Duct Ligation Through Modulation of the STAT3/SOCS3/IRS1 Signaling Pathway</a><br/>J Food Sci. 2019  PMID: 31529802</td><tr/>
<tr><td><strong>074. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6757435/” target=”_blank” rel=”noopener”>TUFT1 promotes metastasis and chemoresistance in triple negative breast cancer through the TUFT1ab5ac1 pathway</a><br/>Cancer Cell Int. 2019  PMID: 31572059</td><tr/>
<tr><td><strong>075. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/31644919/” target=” blank” rel=”noopener”>Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation</a><br/>Cell Rep. 2019  PMID: 31644919</td><tr/>
<tr><td><strong>076. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6876637/” target=” blank” rel=”noopener”>Interplay between …2-chimaerin and Rac1 activity determines dynamic maintenance of long-term memory</a><br/>Nat Commun. 2019  PMID: 31757963</td><tr/>
<tr><td><strong>077. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29155102/” target=” blank” rel=”noopener”>Targeting of Rac1 prevents bronchoconstriction and airway hyperresponsiveness</a><br/>J Allergy Clin Immunol. 2018  PMID: 29155102</td><tr/>
<tr><td><strong>078. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865965″ target=”_blank” rel=”noopener”>COL1A1 promotes metastasis in colorectal cancer by regulating the WNT/PCP pathway</a><br/>Mol Med Rep. 2018  PMID: 29393423</td><tr/>
<tr><td><strong>079. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29444209/” target=” blank” rel=”noopener”>Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart</a><br/>Cardiovasc Res. 2018  PMID: 29444209</td><tr/>
<tr><td><strong>080. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5882563/” target=”_blank” rel=”noopener”>p66Shc Regulates Migration of Castration-Resistant Prostate Cancer Cells</a><br/>Cell Signal. 2018  PMID: 29462661</td><tr/>
<tr><td><strong>081. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832796″ target=”_blank” rel=”noopener”>Podocyte-specific Rac1 deficiency ameliorates podocyte damage and proteinuria in STZ-induced diabetic nephropathy in mice</a><br/>Cell Death Dis. 2018  PMID: 29497040</td><tr/>
<tr><td><strong>082. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916337/” target=”_blank” rel=”noopener”>Protein tyrosine kinase 7 regulates extracellular matrix integrity and mesenchymal intracellular RAC1 and myosin II activities during Wolffian duct morphogenesis</a><br/>Dev Biol. 2018   PMID: 29580943</td><tr/>
<tr><td><strong>083. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29581176/” target=” blank” rel=”noopener”>Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth</a><br/>Cancer Discov. 2018  PMID: 29581176</td><tr/>
<tr><td><strong>084. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949353/” target=”_blank” rel=”noopener”>Complement C3 Affects Rac1 Activity in the Developing Brain</a><br/>Front Mol Neurosci. 2018  PMID: 29867343</td><tr/>
<tr><td><strong>085. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29875261/” target=” blank” rel=”noopener”>The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8 + T cells</a><br/>J Exp Med. 2018  PMID: 29875261</td><tr/>
<tr><td><strong>086. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29884911/” target=”_blank” rel=”noopener”>RAC1-GTP promotes epithelial-mesenchymal transition and invasion of colorectal cancer by activation of STAT3</a><br/>Laboratory Investigation. 2018  PMID: 29884911</td><tr/>
<tr><td><strong>087. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037484/” target=”_blank” rel=”noopener”>Removing physiological motion from intravital and clinical functional imaging data</a><br/>eLife. 2018  PMID: 29985127</td><tr/>
<tr><td><strong>088. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/30005699/” target=”_blank” rel=”noopener”>Rac1 activation links tau hyperphosphorylation and Aβ dysmetabolism in Alzheimer’s disease</a><br/>Acta Neuropathol Commun. 2018  PMID: 30005699</td><tr/>
<tr><td><strong>089. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6036455/” target=”_blank” rel=”noopener”>MicroRNA-650 targets inhibitor of growth 4 to promote colorectal cancer progression via mitogen activated protein kinase signaling</a><br/>Oncol Lett. 2018   PMID: 30008936</td><tr/>
<tr><td><strong>090. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329911/” target=”_blank” rel=”noopener”>The tetraspanin CD82 regulates bone marrow homing and engraftment of hematopoietic stem and progenitor cells</a><br/>Mol Biol Cell. 2018   PMID: 30133344</td><tr/>
<tr><td><strong>091. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27669437/” target=”_blank” rel=”noopener”>The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion</a><br/>Oncogene. 2017  PMID: 27669437</td><tr/>
<tr><td><strong>092. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27927890/” target=” blank” rel=”noopener”>Massively Increased Caries Susceptibility in an Irf6 Cleft Lip/Palate Model</a><br/>J Dent Res. 2017  PMID: 27927890</td><tr/>
<tr><td><strong>093. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224981″ target=”_blank” rel=”noopener”>GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary</a><br/>PLoS Genet. 2017  PMID: 28072828</td><tr/>
<tr><td><strong>094. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410264/” target=”_blank” rel=”noopener”>Biological basis and clinical study of glycogen synthase kinase- 3β-targeted therapy by drug repositioning for glioblastoma</a><br/>Oncotarget. 2017  PMID: 28423558</td><tr/>
<tr><td><strong>095. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28483380/” target=” blank” rel=”noopener”>Rac1 activation in podocytes induces the spectrum of nephrotic syndrome</a><br/>Kidney Int. 2017  PMID: 28483380</td><tr/>
<tr><td><strong>096. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28552735/” target=”_blank” rel=”noopener”>N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis</a><br/>Dev Biol. 2017  PMID: 28552735</td><tr/>
<tr><td><strong>097. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479300″ target=”_blank” rel=”noopener”>High glucose levels promote the proliferation of breast cancer cells through GTPases</a><br/>Breast Cancer (Dove Med Press). 2017  PMID: 28670141</td><tr/>
<tr><td><strong>098. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5645739″ target=”_blank” rel=”noopener”>Role of Nicotinamide N-Methyltransferase in Dorsal Striatum in Cocaine Place Preference</a><br/>Neuropsychopharmacology. 2017  PMID: 28726800</td><tr/>
<tr><td><strong>099. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/28743719/” target=” blank” rel=”noopener”>The atypical receptor CCRL2 is required for CXCR2-dependent neutrophil recruitment and tissue damage</a><br/>Blood. 2017  PMID: 28743719</td><tr/>
<tr><td><strong>100. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29016860/” target=” blank” rel=”noopener”>Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function</a><br/>Hum Mol Genet. 2017  PMID: 29016860</td><tr/>
<tr><td><strong>101. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690821/” target=”_blank” rel=”noopener”>Direction of leukocyte polarization and migration by the phosphoinositide-transfer protein TIPE2</a><br/>Nature Immunology. 2017  PMID: 29058702</td><tr/>
<tr><td><strong>102. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689647/” target=” blank” rel=”noopener”>A PTEN-COL17A1 fusion gene and its novel regulatory role in Collagen XVII expression and GBM malignance</a><br/>Oncotarget. 2017  PMID: 29156757</td><tr/>
<tr><td><strong>103. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/29271742/” target=”_blank” rel=”noopener”>Paxillin facilitates timely neurite initiation on soft-substrate environments by interacting with the endocytic machinery</a><br/>eLife. 2017  PMID: 29271742</td><tr/>
<tr><td><strong>104. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905261″ target=”_blank” rel=”noopener”>Disease-causing mutations of RhoGDIa induce Rac1 hyperactivation in podocytes</a><br/>Small GTPases. 2016  PMID: 26726844</td><tr/>
<tr><td><strong>105. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26775215/” target=” blank” rel=”noopener”>The acetylenic tricyclic bis(cyano enone). TBE-31. targets microtubule dynamics and cell polarity in migrating cells</a><br/>Biochim Biophys Acta. 2016  PMID: 26775215</td><tr/>
<tr><td><strong>106. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835924″ target=”_blank” rel=”noopener”>Dosage-dependent role of Rac1 in podocyte injury</a><br/>Am J Physiol Renal Physiol. 2016  PMID: 26792065</td><tr/>
<tr><td><strong>107. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27008403/” target=”_blank” rel=”noopener”>Rac1/β-Catenin Signalling Pathway Contributes to Trophoblast Cell Invasion by Targeting Snail and MMP9.</a><br/>Cell Physiol Biochem. 2016   PMID: 27008403</td><tr/>
<tr><td><strong>108. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5004713″ target=”_blank” rel=”noopener”>A Stromal Cell–Derived Factor 1a Analogue Improves Endothelial Cell Function in Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome</a><br/>Mol Med. 2016  PMID: 27031787</td><tr/>
<tr><td><strong>109. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27130700/” target=” blank” rel=”noopener”>The RacGAP protein FilGAP is a negative regulator of chemokine-promoted lymphocyte migration</a><br/>FEBS Lett. 2016  PMID: 27130700</td><tr/>
<tr><td><strong>110. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27188212/” target=” blank” rel=”noopener”>Opposing effects of actin signaling and LFA-1 on establishing the affinity threshold for inducing effector T-cell responses in mice</a><br/>Eur J Immunol. 2016  PMID: 27188212</td><tr/>
<tr><td><strong>111. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27329554/” target=”_blank” rel=”noopener”>Inhibition of Rac1 activity in the hippocampus impaired extinction of contextual fear.</a><br/>Neuropharmacology. 2016   PMID: 27329554</td><tr/>
<tr><td><strong>112. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27330411/” target=”_blank” rel=”noopener”>Zinc induces epithelial to mesenchymal transition in human lung cancer H460 cells via superoxide anion-dependent mechanism</a><br/>Cancer Cell Int. 2016  PMID: 27330411</td><tr/>
<tr><td><strong>113. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27425596/” target=”_blank” rel=”noopener”>RAC-LATS1/2 signaling regulates YAP activity by switching between the YAP-binding partners TEAD4 and RUNX3</a><br/>Oncogene. 2016   PMID: 27425596</td><tr/>
<tr><td><strong>114. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27452812/” target=”_blank” rel=”noopener”> Dietary flavonoid luteolin attenuates uropathogenic Escherichia. Coli invasion of the urinary bladder.</a><br/>Biofactors. 2016  PMID: 27452812</td><tr/>
<tr><td><strong>115. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27469030/” target=”_blank” rel=”noopener”>Sur8 mediates tumorigenesis and metastasis in colorectal cancer</a><br/>Exp Mol Med. 2016  PMID: 27469030</td><tr/>
<tr><td><strong>116. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27534887/” target=”_blank” rel=”noopener”>The modulation of MiR-155 and MiR-23a manipulates Klebsiella pneumoniae Adhesion on Human pulmonary Epithelial cells via Integrin α5β1 Signaling</a><br/>Sci Rep. 2016  PMID: 27534887</td><tr/>
<tr><td><strong>117. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019934″ target=”_blank” rel=”noopener”>Gigantol Inhibits Epithelial to Mesenchymal Process in Human Lung Cancer Cells</a><br/>Evid Based Complement Alternat Med. 2016  PMID: 27651818</td><tr/>
<tr><td><strong>118. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206404/” target=”_blank” rel=”noopener”>Rac1 modulates mammalian lung branching morphogenesis in part through canonical Wnt signaling</a><br/>Am J Physiol Lung Cell Mol Physiol. 2016   PMID: 27765763</td><tr/>
<tr><td><strong>119. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27807170/” target=”_blank” rel=”noopener”>Converging. Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses</a><br/>J Neurosci. 2016  PMID: 27807170</td><tr/>
<tr><td><strong>120. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/27999173/” target=” blank” rel=”noopener”>Rac signal adaptation controls neutrophil mobilization from the bone marrow</a><br/>Sci Signal. 2016   PMID: 27999173</td><tr/>
<tr><td><strong>121. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25209090/” target=” blank” rel=”noopener”>miRNA-17 members that target Bmpr2 influence signaling mechanisms important for embryonic stem cell differentiation in vitro and gastrulation in embryos</a><br/>Stem Cells Dev. 2015  PMID: 25209090</td><tr/>
<tr><td><strong>122. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821470/” target=”_blank” rel=”noopener”>LPA-mediated migration of ovarian cancer cells involves translocalization of Gαi2 to invadopodia and association with Src and β-pix</a><br/>Cancer Lett. 2015  PMID: 25451317</td><tr/>
<tr><td><strong>123. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25529012/” target=”_blank” rel=”noopener”>Semaphorin-3F suppresses the stemness of colorectal cancer cells by inactivating Rac1</a><br/>Cancer letters. 2015  PMID: 25529012</td><tr/>
<tr><td><strong>124. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25595279/” target=”_blank” rel=”noopener”>Rac1/Pak1/p38/MMP-2 axis regulates angiogenesis in ovarian cancer</a><br/>Clin Cancer Res. 2015  PMID: 25595279</td><tr/>
<tr><td><strong>125. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25613020/” target=”_blank” rel=”noopener”>Inhibition of Rac1 Activity in the Hippocampus Impairs the Forgetting of Contextual Fear Memory</a><br/>Mol Neurobiol. 2015  PMID: 25613020</td><tr/>
<tr><td><strong>126. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25666619/” target=”_blank” rel=”noopener”>Neuronal apoptosis induced by selective inhibition of Rac GTPase versus global suppression of Rho family GTPases is mediated by alterations in distinct mitogen-activated protein kinase</a><br/>J Biol Chem. 2015  PMID: 25666619</td><tr/>
<tr><td><strong>127. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25874856/” target=”_blank” rel=”noopener”>Fibroblastic Transformation of Corneal Keratocytes by Rac Inhibition is Modulated by Extracellular Matrix Structure and Stiffness</a><br/>J Funct Biomater. 2015  PMID: 25874856</td><tr/>
<tr><td><strong>128. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387585″ target=”_blank” rel=”noopener”>Qian Yang Yu Yin Granule-containing serum inhibits angiotensin II-induced proliferation. reactive oxygen species production. and inflammation in human mesangial cells via an NADPH oxidase 4-dependent pathway</a><br/>BMC Complement Altern Med. 2015  PMID: 25886843</td><tr/>
<tr><td><strong>129. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25912734/” target=”_blank” rel=”noopener”>TIPE2 protein prevents injury-induced restenosis in mice</a><br/>Biochim Biophys Acta. 2015  PMID: 25912734</td><tr/>
<tr><td><strong>130. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25957559/” target=”_blank” rel=”noopener”>Dishevelled-2 regulates cocaine-induced structural plasticity and Rac1 activity in the nucleus accumbens</a><br/>Neurosci Lett. 2015  PMID: 25957559</td><tr/>
<tr><td><strong>131. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26109451/” target=” blank” rel=”noopener”>A bibenzyl from Dendrobium ellipsophyllum inhibits migration in lung cancer cells</a><br/>J Nat Med. 2015  PMID: 26109451</td><tr/>
<tr><td><strong>132. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4522160″ target=”_blank” rel=”noopener”>The cytohesin guanosine exchange factors (GEFs) are required to promote HGF-mediated renal recovery after acute kidney injury (AKI) in mice</a><br/>Physiol Rep. 2015  PMID: 26116550</td><tr/>
<tr><td><strong>133. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4510974/” target=” blank” rel=”noopener”>A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration</a><br/>Nat Commun. 2015  PMID: 26166433</td><tr/>
<tr><td><strong>134. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26184908/” target=”_blank” rel=”noopener”>Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice</a><br/>Cell Death Differ. 2015  PMID: 26184908</td><tr/>
<tr><td><strong>135. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526116/” target=” blank” rel=”noopener”>Truncating mutation in the autophagy gene UVRAG confers oncogenic properties and chemosensitivity in colorectal cancers</a><br/>Nat Commun. 2015  PMID: 26234763</td><tr/>
<tr><td><strong>136. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26299339/” target=”_blank” rel=”noopener”>Rac1 contributes to cerebral ischemia reperfusion-induced injury in mice by regulation of Notch2</a><br/>Neuroscience. 2015.  PMID: 26299339</td><tr/>
<tr><td><strong>137. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549291/” target=” blank” rel=”noopener”>Rac1 Regulates Endometrial Secretory Function to Control Placental Development</a><br/>PLoS Genet. 2015  PMID: 26305333</td><tr/>
<tr><td><strong>138. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741751″ target=”_blank” rel=”noopener”>Sur8/Shoc2 promotes cell motility and metastasis through activation of Ras-PI3K signaling</a><br/>Oncotarget. 2015  PMID: 26384305</td><tr/>
<tr><td><strong>139. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657330/” target=”_blank” rel=”noopener”>Rac1 augments Wnt signaling by stimulating beta-catenin-LEF-1 complex assembly independent of beta-catenin nuclear import</a><br/>J Cell Sci. 2015  PMID: 26403202</td><tr/>
<tr><td><strong>140. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729241/” target=” blank” rel=”noopener”>Rap1 GTPase Inhibits Tumor Necrosis Factor-à-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-?B-Dependent Activation of Rac1</a><br/>Am J Pathol. 2015  PMID: 26476350</td><tr/>
<tr><td><strong>141. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/26725196/” target=”_blank” rel=”noopener”>Cyclic Mechanical Loading Is Essential for Rac1-Mediated Elongation and Remodeling of the Embryonic Mitral Valve</a><br/>Current Biology. 2015  PMID: 26725196</td><tr/>
<tr><td><strong>142. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/18453118/” target=”_blank” rel=”noopener”>Immunofluorescence and Confocal Microscopy of Neutrophils</a><br/>Methods Mol Biol. 2014  PMID: 18453118</td><tr/>
<tr><td><strong>143. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24498424/” target=”_blank” rel=”noopener”>Jak3 Enables Chemokine-Dependent Actin Cytoskeleton Reorganization by Regulating Cofilin and Rac/Rhoa GTPases activation</a><br/>PLoS One. 2014  PMID: 24498424</td><tr/>
<tr><td><strong>144. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24531394/” target=” blank” rel=”noopener”>High incidence of naevi-associated BRAF wild-type melanoma and dysplastic naevi under treatment with the class I BRAF inhibitor vemurafenib</a><br/>Acta Derm Venereol. 2014  PMID: 24531394</td><tr/>
<tr><td><strong>145. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24561795/” target=”_blank” rel=”noopener”>A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1</a><br/>Molecular and Cellular Neuroscience. 2014  PMID: 24561795</td><tr/>
<tr><td><strong>146. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24574051/” target=”_blank” rel=”noopener”>Phosphorylation of α-tubulin by protein kinase C stimulates microtubule dynamics in human breast cells</a><br/>Cytoskeleton. 2014  PMID: 24574051</td><tr/>
<tr><td><strong>147. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383135/” target=”_blank” rel=”noopener”>SHP2 Phosphatase Promotes Mast Cell Chemotaxis toward Stem Cell Factor via Enhancing Activation of the Lyn/Vavac Signaling Axis</a><br/>The Journal of Immunology. 2014  PMID: 24733849</td><tr/>
<tr><td><strong>148. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24752651/” target=”_blank” rel=”noopener”>ROBO1. a tumor suppressor and critical molecular barrier for localized tumor cells to acquire invasive phenotype: Study in African-American and Caucasian prostate cancer models</a><br/>International Journal of Cancer. 2014  PMID: 24752651</td><tr/>
<tr><td><strong>149. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24759106/” target=”_blank” rel=”noopener”>Transcription factors NRF2 and nf-kb are coordinated effectors of the RHO family. GTP binding protein rac1 during inflammation</a><br/>J Biol Chem. 2014   PMID: 24759106</td><tr/>
<tr><td><strong>150. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034421/” target=” blank” rel=”noopener”>PI(4.5)P2 regulates myoblast fusion through Arp2/3 regulator localization at the fusion site</a><br/>Development. 2014  PMID: 24821989</td><tr/>
<tr><td><strong>151. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24859471/” target=” blank” rel=”noopener”>Loss of ARHGDIA expression is associated with poor prognosis in HCC and promotes invasion and metastasis of HCC cells</a><br/>Int J Oncol. 2014  PMID: 24859471</td><tr/>
<tr><td><strong>152. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25149377/” target=” blank” rel=”noopener”>srGAP3 promotes neurite outgrowth of dorsal root ganglion neurons by inactivating RAC1</a><br/>Asian Pac J Trop Med. 2014  PMID: 25149377</td><tr/>
<tr><td><strong>153. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248717/” target=”_blank” rel=”noopener”>Canonical and Non-canonical G-protein Signaling Helps Coordinate Actin Dynamics to Promote Macrophage Phagocytosis of Zymosan</a><br/>Mol Cell Biol. 2014   PMID: 25225330</td><tr/>
<tr><td><strong>154. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25247424/” target=”_blank” rel=”noopener”>p53 Down Regulates PDGF-Induced Formation of Circular Dorsal Ruffles in Rat Aortic Smooth Muscle Cells</a><br/>PLoS One. 2014   PMID: 25247424</td><tr/>
<tr><td><strong>155. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347231″ target=”_blank” rel=”noopener”>TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1</a><br/>J Clin Invest. 2014  PMID: 25295536</td><tr/>
<tr><td><strong>156. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4199721″ target=”_blank” rel=”noopener”>Triclosan Potentiates Epithelial-To-Mesenchymal Transition in Anoikis-Resistant Human Lung Cancer Cells</a><br/>PLoS One. 2014  PMID: 25329306</td><tr/>
<tr><td><strong>157. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254100/” target=”_blank” rel=”noopener”>cAMP controls the restoration of endothelial barrier function after thrombin‐induced hyperpermeability via Rac1 activation</a><br/>Physiological Reports. 2014  PMID: 25344477</td><tr/>
<tr><td><strong>158. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25503138/” target=”_blank” rel=”noopener”>Cisplatin at Sub-toxic Levels Mediates Integrin Switch in Lung Cancer Cells</a><br/>Anticancer Research. 2014  PMID: 25503138</td><tr/>
<tr><td><strong>159. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/25539497/” target=”_blank” rel=”noopener”>Geometry sensing through POR1 regulates Rac1 activity controlling early osteoblast differentiation in response to nanofiber diameter</a><br/>Integr Biol (Camb). 2014  PMID: 25539497</td><tr/>
<tr><td><strong>160. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23148218/” target=”_blank” rel=”noopener”>Neuregulin Mediates F-actin-driven Cell Migration through Inhibition of Protein Kinase D1 via Rac1 Protein</a><br/>J Biol Chem. 2013  PMID: 23148218</td><tr/>
<tr><td><strong>161. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23153508/” target=”_blank” rel=”noopener”>Rac1/PAK1 signaling promotes epithelial-mesenchymal transition of podocytes in vitro via triggering beta-catenin transcriptional activity under high glucose conditions</a><br/>Int J Biochem Cell Biol. 2013   PMID: 23153508</td><tr/>
<tr><td><strong>162. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23175375/” target=”_blank” rel=”noopener”>Reactive Oxygen Species Are Induced by Kaposi’s Sarcoma-Associated Herpesvirus Early during Primary Infection of Endothelial Cells To Promote Virus Entry</a><br/>J Virol. 2013  PMID: 23175375</td><tr/>
<tr><td><strong>163. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23192342/” target=”_blank” rel=”noopener”>Essential Role of Class II Phosphatidylinositol-3-kinase-C2alpha in Sphingosine 1-Phosphate Receptor-1-mediated Signaling and Migration in Endothelial Cells</a><br/>J Biol Chem. 2013  PMID: 23192342</td><tr/>
<tr><td><strong>164. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23321640/s” target=”_blank” rel=”noopener”>PAK-PIX interactions regulate adhesion dynamics and membrane protrusion to control neurite outgrowt</a><br/>J Cell Sci. 2013  PMID: 23321640</td><tr/>
<tr><td><strong>165. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3557251″ target=”_blank” rel=”noopener”>Deficiencies of the Lipid-Signaling Enzymes Phospholipase D1 and D2 Alter Cytoskeletal Organization. Macrophage Phagocytosis. and Cytokine-Stimulated Neutrophil Recruitment</a><br/>PLoS One. 2013  PMID: 23383154</td><tr/>
<tr><td><strong>166. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23429587/” target=” blank” rel=”noopener”>Myocardial Rac1 exhibits partial involvement in thyroxin-induced cardiomyocyte hypertrophy and its inhibition is not sufficient to improve cardiac dysfunction or contractile abnormalities in mouse papillary muscles</a><br/>J Cardiovasc Pharmacol. 2013   PMID: 23429587</td><tr/>
<tr><td><strong>167. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669177/” target=”_blank” rel=”noopener”>A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substrates</a><br/>Autophagy. 2013  PMID: 23439251</td><tr/>
<tr><td><strong>168. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3672376/” target=”_blank” rel=”noopener”>Rac1 is required for matrix metalloproteinase-13 production by chondrocytes in response to fibronectin fragments</a><br/>Arthritis Rheum. 2013  PMID: 23460186</td><tr/>
<tr><td><strong>169. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621493/” target=”_blank” rel=”noopener”>Lis1 mediates planar polarity of auditory hair cells through regulation of microtubule organization</a><br/>Development. 2013  PMID: 23533177</td><tr/>
<tr><td><strong>170. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23699534/” target=”_blank” rel=”noopener”>Fer Protein-Tyrosine Kinase Promotes Lung Adenocarcinoma Cell Invasion and Tumor Metastasis</a><br/>Mol Cancer Res. 2013   PMID: 23699534</td><tr/>
<tr><td><strong>171. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662692/” target=”_blank” rel=”noopener”>Pilus Phase Variation Switches Gonococcal Adherence to Invasion by Caveolin-1-Dependent Host Cell Signaling</a><br/>PLoS Pathog. 2013  PMID: 23717204</td><tr/>
<tr><td><strong>172. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774378/” target=”_blank” rel=”noopener”>ArhGAP15. a Rac-specific GTPase-activating Protein. Plays a Dual Role in Inhibiting Small GTPase Signaling</a><br/>J Biol Chem. 2013  PMID: 23760270</td><tr/>
<tr><td><strong>173. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718375/” target=”_blank” rel=”noopener”>Kalirin-7 Mediates Cocaine-Induced AMPA Receptor and Spine Plasticity. Enabling Incentive Sensitization</a><br/>J Neurosci. 2013  PMID: 23825406</td><tr/>
<tr><td><strong>174. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24019894/” target=”_blank” rel=”noopener”>p21-Activated Kinase (PAK) Regulates Cytoskeletal Reorganization and Directional Migration in Human Neutrophils</a><br/>PLoS One. 2013  PMID: 24019894</td><tr/>
<tr><td><strong>175. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3824649″ target=”_blank” rel=”noopener”>Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells</a><br/>Cell Death Dis. 2013  PMID: 24113182</td><tr/>
<tr><td><strong>176. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823815/” target=” blank” rel=”noopener”>A directional switch of integrin signaling and a new anti-thrombotic strategy</a><br/>Nature. 2013  PMID: 24162846</td><tr/>
<tr><td><strong>177. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/24368807/” target=” blank” rel=”noopener”>JAK tyrosine kinases promote hierarchical activation of Rho and Rap modules of integrin activation</a><br/>J Cell Biol. 2013  PMID: 24368807</td><tr/>
<tr><td><strong>178. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21999233/” target=”_blank” rel=”noopener”>he cooperative action of bacterial fibronectin-binding proteins and secreted proteins promote maximal Campylobacter jejuni invasion of host cells by stimulating membrane ruffling</a><br/>Cell Microbiol. 2012   PMID: 21999233</td><tr/>
<tr><td><strong>179. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22137120/” target=”_blank” rel=”noopener”>Interferon gamma induces actin polymerization. Rac1 activation and down regulates phagocytosis in human monocytic cells</a><br/>Cytokine. 2012  PMID: 22137120</td><tr/>
<tr><td><strong>180. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22203054/” target=” blank” rel=”noopener”>Co-regulation of transcellular and paracellular leak across microvascular endothelium by dynamin and Rac</a><br/>Am J Pathol. 2012  PMID: 22203054</td><tr/>
<tr><td><strong>181. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22349701/” target=” blank” rel=”noopener”>Association of syntenin-1 with M-RIP polarizes Rac-1 activation during chemotaxis and immune interactions</a><br/>J Cell Sci. 2012  PMID: 22349701</td><tr/>
<tr><td><strong>182. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22522400/” target=”_blank” rel=”noopener”>rac1 is essential in cocaine-induced structural plasticity of nucleus accumbens neurons</a><br/>Nat Neurosci. 2012  PMID: 22522400</td><tr/>
<tr><td><strong>183. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22553120/” target=”_blank” rel=”noopener”>Antagonistic activities of Rho and Rac GTPases underlie the transition from neural crest delamination to migration</a><br/>Dev Dyn. 2012   PMID: 22553120</td><tr/>
<tr><td><strong>184. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3395090/” target=” blank” rel=”noopener”>miR-124-regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling</a><br/>EMBO J. 2012  PMID: 22588079</td><tr/>
<tr><td><strong>185. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22623753/” target=”_blank” rel=”noopener”>Interferon-beta Therapy Against EAE Is Effective Only When Development of the Disease Depends on the NLRP3 Inflammasome</a><br/>Sci Signal. 2012  PMID: 22623753</td><tr/>
<tr><td><strong>186. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22695959/” target=”_blank” rel=”noopener”>Rac1 inhibition prevents tissue contraction and MMP mediated matrix remodeling in the conjunctiva</a><br/>Invest Ophthalmol Vis Sci. 2012   PMID: 22695959</td><tr/>
<tr><td><strong>187. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514035″ target=”_blank” rel=”noopener”>Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex</a><br/>J Cell Biol. 2012  PMID: 22891260</td><tr/>
<tr><td><strong>188. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/22936985/” target=”_blank” rel=”noopener”>Rac-induced left ventricular dilation in thyroxin-treated ZmRacD transgenic mice: role of cardiomyocyte apoptosis and myocardial fibrosis</a><br/>PLoS One. 2012  PMID: 22936985</td><tr/>
<tr><td><strong>189. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23185572/” target=”_blank” rel=”noopener”>Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion</a><br/>PLoS One. 2012  PMID: 23185572</td><tr/>
<tr><td><strong>190. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23197717/” target=”_blank” rel=”noopener”>Rac1 controls Schwann cell myelination through cAMP and NF2/merlin </a><br/>J Neurosci. 2012  PMID: 23197717</td><tr/>
<tr><td><strong>191. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/23223289/” target=”_blank” rel=”noopener”>Nerve growth factor-induced formation of axonal filopodia and collateral branches involves the intra-axonal synthesis of regulators of the actin-nucleating Arp2/3 complex</a><br/>J Neurosci. 2012  PMID: 23223289</td><tr/>
<tr><td><strong>192. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21037229/” target=”_blank” rel=”noopener”>Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation</a><br/>Am J Physiol Heart Circ Physiol. 2011   PMID: 21037229</td><tr/>
<tr><td><strong>193. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21358804/” target=”_blank” rel=”noopener”>K-Ras mediated murine epidermal tumorigenesis is dependent upon and associated with elevated Rac1 activity</a><br/>PLoS One. 2011  PMID: 21358804</td><tr/>
<tr><td><strong>194. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062424/” target=” blank” rel=”noopener”>Asymmetric Mbc. active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila</a><br/>Development. 2011  PMID: 21389053</td><tr/>
<tr><td><strong>195. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21563770/” target=”_blank” rel=”noopener”>Aspect ratio determines the quantity of mesoporous silica nanoparticle uptake by a small GTPase-dependent macropinocytosis mechanism</a><br/>ACS Nano. 2011  PMID: 21563770</td><tr/>
<tr><td><strong>196. </strong><a href=”https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129188″ target=”_blank” rel=”noopener”>R-Ras and Rac GTPase Cross-talk Regulates Hematopoietic Progenitor Cell Migration. Homing. and Mobilization</a><br/>J Biol Chem. 2011  PMID: 21572048</td><tr/>
<tr><td><strong>197. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21624123/” target=”_blank” rel=”noopener”>Differential roles of Smad2 and Smad3 in the regulation of TGF-beta1-mediated growth inhibition and cell migration in pancreatic ductal adenocarcinoma cells: control by Rac1</a><br/>Mol Cancer. 2011  PMID: 21624123</td><tr/>
<tr><td><strong>198. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21859816/” target=”_blank” rel=”noopener”>NADPH oxidase activation by hyperglycaemia in cardiomyocytes is independent of glucose metabolism but requires SGLT1</a><br/>Cardiovasc Res. 2011  PMID: 21859816</td><tr/>
<tr><td><strong>199. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21881052/” target=”_blank” rel=”noopener”>Latent KSHV infection increases the vascular permeability of human endothelial cells</a><br/>Blood. 2011   PMID: 21881052</td><tr/>
<tr><td><strong>200. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21893601/” target=”_blank” rel=”noopener”>Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype</a><br/>J Cell Biol. 2011  PMID: 21893601</td><tr/>
<tr><td><strong>201. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21961005/” target=”_blank” rel=”noopener”>Rac1 and Stathmin but Not EB1 Are Required for Invasion of Breast Cancer Cells in Response to IGF-I</a><br/>Int J Cell Biol. 2011  PMID: 21961005</td><tr/>
<tr><td><strong>202. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/21985251/” target=” blank” rel=”noopener”>Ethanol increases p190RhoGAP activity. leading to actin cytoskeleton rearrangements</a><br/>J Neurochem. 2011  PMID: 21985251</td><tr/>
<tr><td><strong>203. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/20610796/” target=”_blank” rel=”noopener”>Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis</a><br/>J Leukoc Biol. 2010  PMID: 20610796</td><tr/>
<tr><td><strong>204. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/20621840/” target=”_blank” rel=”noopener”>Intracellular Ca2+ can compensate for the lack of NADPH oxidase-derived ROS in endothelial cells</a><br/>FEBS Lett. 2010  PMID: 20621840</td><tr/>
<tr><td><strong>205. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/20636139/” target=”_blank” rel=”noopener”>Antioxidants counteract nicotine and promote migration via RacGTP in oral fibroblast cells</a><br/>J Periodontol. 2010  PMID: 20636139</td><tr/>
<tr><td><strong>206. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/20720104/” target=”_blank” rel=”noopener”>Physiological activation of synaptic Rac>PAK (p-21 activated kinase) signaling is defective in a mouse model of fragile X syndrome</a><br/>J Neurosci. 2010  PMID: 20720104</td><tr/>
<tr><td><strong>207. </strong><a href=”https://pubmed.ncbi.nlm.nih.gov/20935639/” target=”_blank” rel=”noopener”>SUMOylation of the GTPase Rac1 is required for optimal cell migration</a><br/>Nat Cell Biol. 2010  PMID: 20935639</td><tr/>
</tbody>
</table>