| 货号: 12269 |
| 产品全名: 人 CX3CL1 蛋白 |
| 规格: 10/50/100 µg |
| 基因符号 NTN;NTT;CXC3;CXC3C;SCYD1;ABCD-3;C3Xkine;fractalkine;neurotactin |
| 目标蛋白: CX3CL1 |
| UNIPROT ID: P78423 |
| 描述: Recombinant human CX3CL1 Protein with C-terminal 6xHis tag |
| 背景: This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017] |
| 物种/宿主: HEK293 |
| 分子量: The protein has a predicted molecular mass of 34.4 kDa after removal of the signal peptide. |
| 分子特征: CX3CL1(Gln25-Gln341) 6×His tag |
| 纯化: The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| 储存和运输: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Human CX3CL1 Protein, His Tag on SDS-PAGE under reducing condition. |
