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DAB2 Rabbit mAb

Anti-DAB2 Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263295

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263295
产品全名:   DAB2 兔单克隆抗体
基因符号   DOC2; DOC-2
UNIPROT ID:   P98082
背景:   This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
抗原:   A synthetic peptide of human DAB2
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R02-4H2
分子量:   Calculated MW: 82 kDa; Observed MW: 96 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using DAB2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of DAB2 in HepG2, U2OS, U251 lysates using DAB2 antibody.
           引用文献