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Phospho-IRE1 (Ser724) Rabbit mAb

Anti-Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263172

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263172
产品全名:   Phospho-IRE1 (Ser724) 兔单克隆抗体
基因符号   ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a
UNIPROT ID:   O75460
背景:   Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
抗原:   A synthetic phosphopeptide corresponding to residues surrounding Ser724 of human IRE1
经过测试的应用:   WB,IP
推荐稀释比:   WB: 1/500-1/1000 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R05-6E7
分子量:   Calculated MW: 110 kDa; Observed MW: 110 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human
Modification:   Phosphorylated
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-IRE1 (Ser724) in MCF-7, HL-60 lysates using Phospho-IRE1 (Ser724) antibody.
           引用文献