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Topoisomerase I Rabbit mAb

Anti-Topoisomerase I Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N263009

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N263009
产品全名:   Topoisomerase I 兔单克隆抗体
基因符号   TOP1; DNA topoisomerase 1; DNA topoisomerase I
UNIPROT ID:   P11387
背景:   Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3′-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5′-OH DNA strand.
抗原:   A synthetic peptide of human Topoisomerase I
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R02-2H9
分子量:   Calculated MW: 91 kDa; Observed MW: 91 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Topoisomerase I(green) in Hela using Topoisomerase I antibody,and DAPI(blue)

Western blot analysis of Topoisomerase I in K562, rat Brain, C6, 3T3, Hela lysates using Topoisomerase I antibody.

Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Topoisomerase I antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
           引用文献