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Lamin A/C Rabbit mAb

Anti-Lamin A/C Rabbit Monoclonal Antibody
5/5

¥2,850.00

货号:N262455

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N262455
产品全名:   Lamin A/C 兔单克隆抗体
基因符号   LMNA; LMN1; Prelamin-A/C
UNIPROT ID:   P02545
背景:   Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Play an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics.Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.
抗原:   A synthetic peptide of human Lamin A/C
经过测试的应用:   WB,IHC-F,IHC-P,ICC/IF,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Monoclonal
克隆编号:   R06-7H5
分子量:   Calculated MW: 74 kDa; Observed MW: 74,63 kDa
亚型:   IgG
纯化:   Affinity Purified
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   apoptosis – Caspase family
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of Lamin A/C(green) in Hela using Lamin A/C antibody,and DAPI(blue)

Western blot analysis of Lamin A/C in rat heart, rat skeletal muscle lysates using Lamin A/C antibody.

Western blot analysis of Lamin A/C in 3T3, Hela lysates using Lamin A/C antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Lamin A/C antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
           引用文献