武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N262318 | ||||
产品全名: HDAC2 兔单克隆抗体 | ||||
基因符号 HDAC2; Histone deacetylase 2; HD2 | ||||
UNIPROT ID: Q92769 | ||||
背景: In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. | ||||
抗原: Recombinant protein of human HDAC2 | ||||
经过测试的应用: WB,IHC-F,IHC-P,ICC/IF,IP | ||||
推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20 | ||||
种属反应性: Rabbit | ||||
克隆性: Rabbit Monoclonal | ||||
克隆编号: R06-4E4 | ||||
分子量: Calculated MW: 55 kDa; Observed MW: 60 kDa | ||||
亚型: IgG | ||||
纯化: Affinity Purified | ||||
种属反应性: Human, Mouse and Rat | ||||
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
研究领域: Epigenetics&Histone Acetylation | ||||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||||
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