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STK3 Rabbit pAb

Anti-STK3 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225669

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225669
产品全名:   STK3 兔多抗
基因符号   STK3; Mess1; MST-2; MST2; Serine/threonine kinase 3; KRS1; STE20-like kinase MST2
UNIPROT ID:   Q13188
背景:   Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
抗原:   A synthesized peptide derived from human STK3
经过测试的应用:   WB,IHC-P,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 56 kDa; Observed MW: 56 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human, Mouse and Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human kidney using STK3 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of STK3 in HeLa lysates using STK3 antibody.
           引用文献