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Phospho-eIF4E (Ser209) Rabbit pAb

Anti-Phospho-eIF4E (Ser209) Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:N225613

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N225613
产品全名:   Phospho-eIF4E (Ser209) 兔多抗
基因符号   EIF4E; EIF4EL1; EIF4F; Eukaryotic translation initiation factor 4E; eIF-4E; eIF4E; eIF-4F 25 kDa subunit; mRNA cap-binding 蛋白
UNIPROT ID:   P06730
背景:   eIF4E, a protein modulates translation of maternal mRNAs in early embryos before the onset of zygotic transcription. eIF4E also influences the overall rate of translation. eIF4E binds to the 7 methyl GTP cap structure of eukaryotic mRNAs. Phosphorylation of eIF4E on serine 209 regulates the affinity of this protein for the 7 methyl GTP cap and/or RNA. Phosphorylation also enhances the interaction of eIF4E with eIF4G, which form a complex known as eIF4F. eIF4E phosphorylation is correlated with increased translational rate in a number of cell types.
抗原:   A synthesized peptide derived from human Phospho-eIF4E (S209)
经过测试的应用:   WB,IHC-P,ICC/IF,IP
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
分子量:   Calculated MW: 25 kDa; Observed MW: 25 kDa
亚型:   IgG
纯化:   Affinity Chromatography
种属反应性:   Human, Mouse and Rat
Modification:   Phosphorylated
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded mouse kidney using Phospho-eIF4E (S209) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of eIF4E (Phospho-S209) in (1) HEK293 lysates; (2) mouse spleen lysates using Phospho-eIF4E (Ser209) antibody.
           引用文献