| 货号: N225420 |
| 产品全名: Phospho-kappa Opioid Receptor (Ser369) 兔多抗 |
| 基因符号 OPRK1; OPRK; Kappa-type opioid receptor; K-OR-1; KOR-1 |
| UNIPROT ID: P41145 |
| 背景: Endogenous opioid peptides and opiates, like morphine, transmit their pharmacological effects through membrane bound opioid receptors. Pharmacological studies and molecular cloning have led to the identification of three different types of opioid receptor, mu-type, delta-type and kappa-type, also designated MOR-1, DOR-1 and KOR-1, respectively. MOR-1 is a receptor for beta-endorphin, DOR-1 is a receptor for enkephalins, and KOR-1 is a receptor for dynorphins.The three opioid receptor types are highly homologous and belong to the superfamily of G-protein-coupled receptors. Opioid receptors have been shown to modulate a range of brain functions, including instinctive behavior and emotions. This regulation is thought to involve the inhibition of neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. |
| 抗原: The antiserum was produced against synthesized peptide derived from KOR-1 around the phosphorylation site of Ser369. AA range:331-380 |
| 经过测试的应用: WB,IHC-P,ELISA |
| 推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 分子量: Calculated MW: 43 kDa; Observed MW: 43 kDa |
| 亚型: IgG |
| 纯化: Affinity Chromatography |
| 种属反应性: Mouse,Rat |
| Modification: Phosphorylated |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
| 研究领域: Neuroscience |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin-embedded Human brain using Phospho-kappa Opioid Receptor (Ser369) antibody. High-pressure and temperature Tris-EDTA pH 8.0 was used for antigen retrieval.Sample with blocking peptide on the right. | 
Western blot analysis of Phospho-kappa Opioid Receptor (Ser369) in various lysates using Phospho-kappa Opioid Receptor (Ser369) antibody. | 
Western blot analysis of Phospho-kappa Opioid Receptor (Ser369) in rat kidney lysates using Phospho-KOR1 (S369) antibody. | 
Western blot analysis of Phospho-kappa Opioid Receptor (Ser369) in NIH/3T3 lysates using Phospho-kappa Opioid Receptor (Ser369) antibody.The lane on the right is blocked with the Phospho- peptide. |
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