武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N261378 | ||||||
产品全名: GRP78 BiP (6H7) 小鼠单抗 | ||||||
基因符号 HSPA5; GRP78; 78 kDa glucose-regulated protein; GRP-78; Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP | ||||||
UNIPROT ID: P11021 | ||||||
背景: When Chinese hamster K12 cells are starved of glucose, the synthesis of several proteins, called glucose-regulated proteins (GRPs), is markedly increased. Hendershot et al. (1994) (PubMed 8020977) pointed out that one of these, GRP78 (HSPA5), also referred to as ‘immunoglobulin heavy chain-binding protein’ (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). | ||||||
抗原: Synthetic peptide conjugated to KLH. | ||||||
经过测试的应用: WB,IHC-P | ||||||
推荐稀释比: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||||||
种属反应性: Mouse | ||||||
克隆性: Mouse Monoclonal | ||||||
克隆编号: 6H7-4B1-9H4 | ||||||
分子量: Calculated MW: 72 kDa; Observed MW: 78 kDa | ||||||
亚型: IgG1 | ||||||
纯化: Affinity Purified | ||||||
种属反应性: Human, Mouse and Rat | ||||||
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||||
研究领域: Tags & Cell Markers | ||||||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||||||
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