武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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CD45 Mouse mAb

Anti-CD45 Mouse Monoclonal Antibody
5/5

¥2,850.00

货号:N261203

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   N261203
产品全名:   CD45 小鼠单抗
基因符号   PTPRC; CD45; Receptor-type tyrosine-protein phosphatase C; Leukocyte common antigen; L-CA; T200; CD antigen CD45
UNIPROT ID:   P08575
背景:   The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
抗原:   Purified recombinant fragment of human PTPRC (AA: 928-989) expressed in E. Coli.
经过测试的应用:   WB,IHC-P
推荐稀释比:   WB: 1/500-1/1000 IHC: 1/50-1/100
种属反应性:   Mouse
克隆性:   Mouse Monoclonal
克隆编号:   5D3A3
分子量:   Calculated MW: 147 kDa; Observed MW: 180-240kDa
亚型:   IgG1
纯化:   Affinity Purified
种属反应性:   Human,Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded esophageal cancer tissues using PTPRC antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded breast cancer tissues using PTPRC antibody with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of PTPRC antibody in Ramos, Raw264.7 lysates using PTPRC antibody.
           引用文献