武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处
武汉费斯德生物科技有限公司是美国NewEast Biosciences在中国的办事处。NewEast Biosciences 在十二年前率先研发俩种独特的抗体。这俩种抗体仅仅识别活性的GTP酶或者突变的Oncogene。 GTP酶涉及(1)响应细胞表面受体激活的信号转导,包括跨膜受体,例如介导味觉、嗅觉和视觉的那些,(2)核糖体的蛋白质生物合成,(3)调节细胞分化、增殖、分裂和运动,(4)蛋白质通过膜的易位,(5)细胞内囊泡的运输,以及囊泡介导的分泌和摄取,通过GTP酶控制囊泡外壳组装。Oncogene侧是诱发癌症的基因。
我公司将向你提供以下的独一无二的三种抗体或者试剂盒: (1) 仅识别 GTP酶的活性构型的产品, 它可以让你能够量化GTP酶在细胞中的活性和分布。(2) 识别突变 Oncogene蛋白, 但不认识相应野生型的抗体。 (3) 对 cAMP 和 cGMP 具有超亲和力(无需乙酰化)ELISA检测试剂盒。这些产品被将近一千篇同行评议的文章所引用。
¥2,850.00
货号: N261176 | ||||
产品全名: MLH1 (4C1) 小鼠单抗 | ||||
基因符号 MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1 | ||||
UNIPROT ID: P40692 | ||||
背景: This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined. | ||||
抗原: Purified recombinant fragment of MLH1 (aa381-483) expressed in E. Coli. | ||||
经过测试的应用: WB,ICC/IF | ||||
推荐稀释比: WB: 1/500-1/1000 IF: 1/50-1/200 | ||||
种属反应性: Mouse | ||||
克隆性: Mouse Monoclonal | ||||
克隆编号: 4C1-D9-C7 | ||||
分子量: Calculated MW: 85 kDa; Observed MW: 85 kDa | ||||
亚型: IgG1 | ||||
纯化: Ascitic Fluid | ||||
种属反应性: Human,Monkey | ||||
成分: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||||
研究领域: Epigenetics and Nuclear Signaling | ||||
储存和运输: Store at -20°C. Avoid repeated freezing and thawing | ||||
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