武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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GPER1 Rabbit pAb

Anti-GPER1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S222055

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S222055
产品全名:   GPER1 兔多抗
基因符号   mER; CEPR; GPER; DRY12; FEG-1; GPR30; LERGU; LyGPR; CMKRL2; LERGU2; GPCR-Br
UNIPROT ID:   Q99527 (Gene Accession – NP_001496 )
背景:   This gene encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum and a member of the G-protein coupled receptor 1 family. This receptor binds estrogen and activates multiple downstream signaling pathways, leading to stimulation of adenylate cyclase and an increase in cyclic AMP levels, while also promoting intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. This receptor has been shown to play a role in diverse biological processes, including bone and nervous system development, metabolism, cognition, male fertility and uterine function.
抗原:   Synthetic peptide of human GPER1
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 25-50; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer using 222055(GPER1 Antibody) at a dilution of 1/25(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer is first treated with the synthetic peptide and then with 222055(Anti-GPER1 Antibody) at dilution 1/25.
           引用文献