| 货号: S221924 |
| 产品全名: DUSP27 兔多抗 |
| 基因符号 |
| UNIPROT ID: Q5VZP5 (Gene Accession – NP_001073895 ) |
| 背景: Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK and p38. DUSP27 (dual specificity phosphatase 27), also known as FMDSP or DUPD1 (dual specificity phosphatase and pro isomerase domain containing 1), is a 220 amino acid cytoplasmic protein that belongs to the protein-tyrosine phosphatase family. Expressed in skeletal muscle, liver and adipose tissue, DUSP27 may play a role in energy metabolism. The gene encoding DUSP27 is referred to as DUPD1 and maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. |
| 抗原: Synthetic peptide of human DUSP27 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 25-100; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221924(DUSP27 Antibody) at a dilution of 1/25(Cytoplasm or Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221924(Anti-DUSP27 Antibody) at dilution 1/25. | 
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 221924(Anti-DUSP27 Antibody) at a dilution of 1/25. | 
In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D263745(Anti-DUSP27 Antibody) at dilution 1/25. |
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