| 货号: S221878 |
| 产品全名: DAGLA 兔多抗 |
| 基因符号 NSDDR; C11orf11; DAGLALPHA; DAGL(ALPHA) |
| UNIPROT ID: Q9Y4D2 (Gene Accession – NP_006124 ) |
| 背景: Members of the AB hydrolase superfamily have diverse catalytic functions and play a crucial role in the metabolism of lipids. DAGLà (diacylglycerol lipase alpha), also known as NSDDR or C11orf11, is a 1,042 amino acid multi-pass membrane protein that belongs to the AB hydrolase superfamily. Highly expressed in brain and pancreas, DAGLà uses calcium as a cofactor to catalyze the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), a reaction that is required for axonal growth and for retrograde synaptic signaling at mature synapses. DAGLà functions as at optimal pH of 7 and its activity is inhibited by p-hydroxy-mercuri-benzoate and HgCl2. The gene encoding DAGLà maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. |
| 抗原: Synthetic peptide of human DAGLA |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 25-100; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Metabolism, Neuroscience, Cardiovascular |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 221878(DAGLA Antibody) at a dilution of 1/20(Cytoplasm or Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 221878(Anti-DAGLA Antibody) at dilution 1/20. | 
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using 221878(Anti-DAGLA Antibody) at a dilution of 1/20. | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with synthetic peptide and then with D263668(Anti-DAGLA Antibody) at dilution 1/20. |
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