| 货号: S221463 |
| 产品全名: MAGEB5 兔多抗 |
| 基因符号 CT3.3; MAGE-B5 |
| UNIPROT ID: Q9BZ81 (Gene Accession – NP_001258681 ) |
| 背景: The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B5 (melanoma-associated antigen B5), also known as CT3.3 (cancer/testis antigen 3.3), is a 275 amino acid protein that contains one MAGE domain and is expressed in testis. The gene encoding MAGE-B5 maps to human chromosome ,x which consists of about 153 million base pairs and nearly 1,000 genes. Color blindness, hemophilia and Duchenne muscular dystrophy are well known X chromosome-linked conditions which affect males more frequently, as males carry a single X chromosome. |
| 抗原: Synthetic peptide of human MAGEB5 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 20-100; ELISA: 5000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 221463(MAGEB5 Antibody) at a dilution of 1/20(Cytoplasm and Cell membrane). | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 221463(Anti-MAGEB5 Antibody) at dilution 1/20. | 
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 221463(Anti-MAGEB5 Antibody) at a dilution of 1/20. | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D263064(Anti-MAGEB5 Antibody) at dilution 1/20. |
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