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SLC7A11 Rabbit pAb

Anti-SLC7A11 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S221146

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S221146
产品全名:   SLC7A11 兔多抗
基因符号   xCT; CCBR1
UNIPROT ID:   Q9UPY5 (Gene Accession – NP_055146 )
背景:   This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.
抗原:   Synthetic peptide of human SLC7A11
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-100;WB: 1000-5000;ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Metabolism, Cell Biology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human cervical cancer tissue using 221146(SLC7A11 Antibody) at a dilution of 1/50(Cytoplasm and Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human cervical cancer tissue is first treated with the synthetic peptide and then with 221146(Anti-SLC7A11 Antibody) at dilution 1/50.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: HepG2 and 293T cell lysates;
Primary antibody: 221146(SLC7A11 Antibody) at dilution 1/1600;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 1 minute
           引用文献