| 货号: S221108 |
| 产品全名: VPS26A 兔多抗 |
| 基因符号 HB58; PEP8A; VPS26; Hbeta58 |
| UNIPROT ID: O75436 (Gene Accession – NP_004887 ) |
| 背景: This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric comple,x termed the retromer comple,x involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| 抗原: Synthetic peptide of human VPS26A |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 25-100;WB: 500-2000;ELISA: 2000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Signal Transduction |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 221108(VPS26A Antibody) at a dilution of 1/35(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 221108(Anti-VPS26A Antibody) at dilution 1/35. | 
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 221108(Anti-VPS26A Antibody) at a dilution of 1/35. | 
In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with synthetic peptide and then with D262484(Anti-VPS26A Antibody) at dilution 1/35. | 
Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-7: Human placenta tissue, PC3 cells, Human fetal liver tissue, HepG2 cells, Hela cells, A431 cells, 293T cells;
Primary antibody: 221108(VPS26A Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 40 seconds | |
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