| 货号: S220849 |
| 产品全名: RBM38 兔多抗 |
| 基因符号 RNPC1; SEB4B; SEB4D; HSRNASEB; dJ800J21.2 |
| UNIPROT ID: Q9H0Z9 (Gene Accession – NP_059965 ) |
| 背景: RBM38 is a cell cycle protein found in the cytosol and the nucleus that exists as two alternatively spliced isoforms, 1 (RNPC1a) and 2 (RNPC1b), of 239 and 121 amino acids, respectively. Independent of p53 expression, RBM38 isoform 1 induces cell cycle arrest in G1 phase through maintaining transcript stability at the 3?-UTR of p21, a regulator of cell cycle progression at S phase. RBM38 is also an mRNA splicing factor that regulates the expression of FGFR2. RBM38 contains one RRM (RNA recognition motif) domain. |
| 抗原: Synthetic peptide of human RBM38 |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 50-300; ELISA: 2000-10000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling, Cancer, Stem Cells, Developmental Biology |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 220849(RBM38 Antibody) at a dilution of 1/45(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 220849(Anti-RBM38 Antibody) at dilution 1/45. | 
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 220849(Anti-RBM38 Antibody) at a dilution of 1/45. | 
In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with synthetic peptide and then with D262114(Anti-RBM38 Antibody) at dilution 1/45. |
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