| 货号: S220811 |
| 产品全名: PNN 兔多抗 |
| 基因符号 DRS; DRSP; SDK3; memA |
| UNIPROT ID: Q9H307 (Gene Accession – NP_002678 ) |
| 背景: Pinin is a desmosomal associated protein involved with the maintenance of cell to cell adhesion of the epithelium. Pinin is a widespread protein and has been shown to play an important role in cell adhesion through its interaction with nuclear complexes. Pinin is also involved in pre-mRNA splicing through its interactions with a C-terminal RS domain of Cyclophilin G, a Moca type nuclear cyclophilin. Pinin becomes nuclear during the early stages of embryonic development and remains so throughout the entire period. Defects or lack of Pinin can be lethal at perinatal stages and causes defects in the cardiac outflow tract, axial skeleton, palate and dorsal dermis. |
| 抗原: Synthetic peptide of human PNN |
| 经过测试的应用: ELISA, IHC |
| 推荐稀释比: IHC: 50-200; ELISA: 2000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Epigenetics and Nuclear Signaling, Cancer |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 220811(PNN Antibody) at a dilution of 1/50(Nucleus). | 
In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the synthetic peptide and then with 220811(Anti-PNN Antibody) at dilution 1/50. | 
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220811(Anti-PNN Antibody) at a dilution of 1/50. | 
In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D262053(Anti-PNN Antibody) at dilution 1/50. |
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