武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

邮箱:2716620741@qq.com

咨询:027 – 63497286 

RCAN1 Rabbit pAb

Anti-RCAN1 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S220319

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S220319
产品全名:   RCAN1 兔多抗
基因符号   CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
UNIPROT ID:   P53805 (Gene Accession – NP_004405 )
背景:   The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
抗原:   Synthetic peptide of human RCAN1
经过测试的应用:   ELISA, WB, IHC
推荐稀释比:   IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 220319(RCAN1 Antibody) at a dilution of 1/45(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 220319(Anti-RCAN1 Antibody) at dilution 1/45.

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using 220319(Anti-RCAN1 Antibody) at a dilution of 1/45.

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with synthetic peptide and then with D261343(Anti-RCAN1 Antibody) at dilution 1/45.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-2: Mouse heart tissue, Mouse brain tissue;
Primary antibody: 220319(RCAN1 Antibody) at dilution 1/500;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
           引用文献