| 货号: S220293 |
| 产品全名: ACE 兔多抗 |
| 基因符号 DCP; ICH; ACE1; DCP1; CD143; MVCD3 |
| UNIPROT ID: P12821 (Gene Accession – NP_000780 ) |
| 背景: This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. |
| 抗原: Synthetic peptide of human ACE |
| 经过测试的应用: ELISA, WB, IHC |
| 推荐稀释比: IHC: 100-300;WB: 200-1000;ELISA: 2000-5000 |
| 种属反应性: Rabbit |
| 克隆性： Rabbit Polyclonal |
| 亚型: Immunogen-specific rabbit IgG |
| 纯化: Antigen affinity purification |
| 种属反应性: Human, Mouse, Rat |
| 成分: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol |
| 研究领域: Metabolism, Cancer, Cardiovascular, Cell Biology, Stem Cells |
| 储存和运输: Store at -20°C. Avoid repeated freezing and thawing |
Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 220293(ACE Antibody) at a dilution of 1/70(Cytoplasm). | 
In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 220293(Anti-ACE Antibody) at dilution 1/70. | 
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 220293(Anti-ACE Antibody) at a dilution of 1/70. | 
In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with synthetic peptide and then with D261280(Anti-ACE Antibody) at dilution 1/70. | 
Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-3: Human ileum adenocarcinoma tissue, Human testis tissue, Human prostate tissue;
Primary antibody: 220293(ACE Antibody) at dilution 1/240;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 30 seconds | |
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