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LILRB3 Rabbit pAb

Anti-LILRB3 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219870

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219870
产品全名:   LILRB3 兔多抗
基因符号   HL9, ILT5, LIR3, PIRB, CD85A, ILT-5, LIR-3, LILRA6
UNIPROT ID:   O75022 (Gene Accession – NP_006855 )
背景:   This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene.
抗原:   Synthetic peptide of human LILRB3
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 15-50; ELISA: 1000-2000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Immunology
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human breast cancer tissue using 219870(LILRB3 Antibody) at a dilution of 1/20(Cytoplasm, Cell membrane).

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with the synthetic peptide and then with 219870(Anti-LILRB3 Antibody) at dilution 1/20.
           引用文献