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CRACR2A Rabbit pAb

Anti-CRACR2A Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219378

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219378
产品全名:   CRACR2A 兔多抗
基因符号   EFCAB4B
UNIPROT ID:   Q9BSW2 (Gene Accession – BC004524 )
背景:   Ca2+-binding protein that plays a key role in store-operated Ca2+ entry (SOCE) in T-cells by regulating CRAC channel activation. Acts as a cytoplasmic calcium-sensor that facilitates the clustering of ORAI1 and STIM1 at the junctional regions between the plasma membrane and the endoplasmic reticulum upon low Ca2+concentration. It thereby regulates CRAC channel activation, including translocation and clustering of ORAI1 and STIM1. Upon increase of cytoplasmic Ca2+resulting from opening of CRAC channels, dissociates from ORAI1 and STIM1, thereby destabilizing the ORAI1-STIM1 complex.
抗原:   Fusion protein of human CRACR2A
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human brain tissue using 219378(CRACR2A Antibody) at a dilution of 1/60(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human brain tissue is first treated with the fusion protein and then with 219378(Anti-CRACR2A Antibody) at dilution 1/60.
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