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CD59 Rabbit pAb

Anti-CD59 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219197

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219197
产品全名:   CD59 兔多抗
基因符号   1F5; EJ16; EJ30; EL32; G344; MIN1; MIN2; MIN3; MIRL; HRF20; MACIF; MEM43; MIC11; MSK21; 16.3A5; HRF-20; MAC-IP; p18-20
UNIPROT ID:   P13987 (Gene Accession – BC001506 )
背景:   This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack comple,x whereby it binds complement C8 and/or C9 during the assembly of this comple,x thereby inhibiting the incorporation of multiple copies of C9 into the comple,x which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.
抗原:   Fusion protein of human CD59
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 200-300; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Cardiovascular, Immunology, Stem Cells
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 219197(CD59 Antibody) at a dilution of 1/160(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 219197(Anti-CD59 Antibody) at dilution 1/160.
           引用文献