武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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ELF3 Rabbit pAb

Anti-ELF3 Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S219087

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S219087
产品全名:   ELF3 兔多抗
基因符号   ERT; ESX; EPR-1; ESE-1
UNIPROT ID:   P78545 (Gene Accession – BC003569 )
背景:   Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).
抗原:   Fusion protein of human ELF3
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 50-300; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Epigenetics and Nuclear Signaling
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 219087(ELF3 Antibody) at a dilution of 1/95(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 219087(Anti-ELF3 Antibody) at dilution 1/95.
           引用文献