武汉费斯德生物科技有限公司, NewEast Biosciences 中国办事处

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NGEF Rabbit pAb

Anti-NGEF Rabbit Polyclonal Antibody
5/5

¥2,850.00

货号:S218909

规格: 100 微升

库存状态:In Stock

           产品描述          
货号:   S218909
产品全名:   NGEF 兔多抗
基因符号   EPHEXIN; ARHGEF27
UNIPROT ID:   Q8N5V2 (Gene Accession – BC031573 )
背景:   Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
抗原:   Fusion protein of human NGEF
经过测试的应用:   ELISA, IHC
推荐稀释比:   IHC: 40-200; ELISA: 5000-10000
种属反应性:   Rabbit
克隆性:   Rabbit Polyclonal
亚型:   Immunogen-specific rabbit IgG
纯化:   Antigen affinity purification
种属反应性:   Human, Mouse, Rat
成分:   PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
研究领域:   Signal Transduction, Neuroscience
储存和运输:   Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human tonsil tissue using 218909(NGEF Antibody) at a dilution of 1/35(Cytoplasm or Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with the fusion protein and then with 218909(Anti-NGEF Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using 218909(Anti-NGEF Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with fusion protein and then with D225483(Anti-NGEF Antibody) at dilution 1/35.
           引用文献